| Autor: |
G, Corso, E, Bottacchi, A, Brusa, M Di, Benedetto, G, Giardini, C, Lia, M, Reggiani, M, Veronese Morosini |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Acta neurologica Scandinavica. 122(3) |
| ISSN: |
1600-0404 |
| Popis: |
We investigated the relationship between C-reactive protein (CRP)-values in the acute phase of stroke and the risk of further fatal and non-fatal ischemic events.We analysed 462 consecutive incident ischemic strokes. Patients were divided into two subgroups on the basis of a CRP cut-off level of 9 mg/l. Primary end points were any new vascular fatal and non-fatal event recorded during the follow-up period.During a follow-up of 2.27 years, in 132 patients occurred a primary end point. Patients with CRP valuesor = 9 mg/l had more frequently primary end point. The hazard ratio (HR) for cardiovascular events was 3.59; 1.93 for cerebrovascular events; 7.43 for vascular deaths and 5.78 for death from any cause. Cox proportional hazard multivariate analysis identified CRP valuesor = 9 (HR = 4.19, 95% CI: 1.85-9.50, P = 0.001), the lack of secondary prevention therapy at discharge (HR = 4.35, 95% CI: 1.87-10.1, P = 0.001), age70 years (HR = 3.09, 95% CI: 1.04-9.24, P = 0.04) as independent predictors of fatal events.CRP levelsor = 9 mg/l, evaluated in incident ischemic stroke within 24 h, predict a higher risk of further ischemic events and mortality. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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