Melatonin enhances cisplatin-induced cell death through inhibition of DERL1 in mesenchymal-like CD44

Autor: Hideo, Shigeishi, Sho, Yokoyama, Hiroshi, Murodumi, Miyuki, Sakuma, Shohei, Fukada, Satoshi, Okuda, Nao, Yamakado, Shigehiro, Ono, Masaaki, Takechi, Kouji, Ohta
Rok vydání: 2021
Předmět:
Zdroj: Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES. 51(3)
ISSN: 1600-0714
Popis: Melatonin is a hormone that is primarily produced in the pineal gland and is involved in wide range of biological functions. However, the impact of melatonin on chemotherapy-induced cell death remains to be elucidated in oral squamous cell carcinoma (OSCC) cells. The objective of this study was to clarify the role of melatonin in cisplatin-induced cytotoxicity in CD44CD44CD44Melatonin plays a vital role in promoting cisplatin-induced cytotoxicity in mesenchymal-like CD44
Databáze: OpenAIRE