| Autor: |
Marie, Devreux, Céline, Henoumont, Fabienne, Dioury, Sébastien, Boutry, Olivier, Vacher, Luce Vander, Elst, Marc, Port, Robert N, Muller, Olivier, Sandre, Sophie, Laurent |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Inorganic chemistry. 60(6) |
| ISSN: |
1520-510X |
| Popis: |
Magnetic resonance imaging (MRI) has a leading place in medicine as an imaging tool of high resolution for anatomical studies and diagnosis of diseases, in particular for soft tissues that cannot be accessible by other modalities. Many research works are thus focused on improving the images obtained with MRI. This technique has indeed poor sensitivity, which can be compensated by using a contrast agent (CA). Today, the clinically approved CAs on market are solely based on gadolinium complexes that may induce nephrogenic systemic fibrosis for patients with kidney failure, whereas more recent studies on healthy rats also showed Gd retention in the brain. Consequently, researchers try to elaborate other types of safer MRI CAs like manganese-based complexes. In this context, the synthesis of Mn |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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