| Autor: |
Nafiseh, Ghorbani, Mehdi, Assmar, Nour, Amirmozafari, Khosrow, Issazadeh |
| Rok vydání: |
2020 |
| Zdroj: |
Iranian journal of public health. 50(7) |
| ISSN: |
2251-6093 |
| Popis: |
Bacterial spores are among the most efficient vaccine delivery vehicles. Because of their safety and efficacy,This work was performed during 2018-2019 in Islamic Azad University of Lahijan. FliC protein was recombinantly expressed inFliC protein was successfully expressed and purified. Sporulation was controlled by phase-contrast microscopy. Serum IgG assay showed significant stimulation of the mice's humoral immune system. Immunized mice were able to resist bacterial infection.The results showed the efficiency of spores as natural adjuvants for the stimulation of mice immune system. The formulation can be exploited for the delivery of recombinant vaccines against bacterial pathogens. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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