[Drug-induced acute arterial occlusion]

Autor: T, Carrel, B, Carrel, H, Jutzi, B, Nachbur
Jazyk: francouzština
Rok vydání: 1990
Předmět:
Zdroj: Helvetica chirurgica acta. 57(1)
ISSN: 0018-0181
Popis: An acute ischemia has almost its origin in a mechanical obstruction of the vessel caused by embolus, thrombose or dissection. An ischemia caused by medicament, excepted the erronated intraarterial injection of vasoconstrictive medicament, is very seldom encountered in the clinic. We describe the case of a young woman who was referred to our clinic for investigation and treatment of an acute ischemia of both limbs. In her past medical history she was treated because of a liver insufficiency occurring after a spontaneous abortion and received methylergometrine (Methergin) for uterine stimulation. Because of this unusual manifestation in a young patient with a complicated past medical history we considered the possibility of a drug induced ischemia caused by ergotamine-derivate. The rapid recovering after treatment with chlorpromazine and nifedipine confirmed the suspected diagnosis. A well defined therapy of this rare complication has not been described; vasodilatators, nitroglycerin, calcium-antagonists and even streptokinase and balloon dilatation are proposed.
Databáze: OpenAIRE