[The estimation of the level of mutations at the glycophorin A locus in subjects exposed to the chronic action of ionizing radiation]

Autor: L M, Rozhdestvenskiĭ, N D, Okladnikova, T N, Smirnova, V I, Tel'nov, P G, Pleshanov, P, Kato, R G, Langlois
Rok vydání: 1998
Předmět:
Zdroj: Radiatsionnaia biologiia, radioecologiia. 38(3)
ISSN: 0869-8031
Popis: 11 persons, who had been irradiated chronically at low dose rate under occupational conditions in 1950s in doses 220-581 cGy according data of individual film dosimeters, and 5 control persons were examined regarding the level of glycophorin A (GPA) mutation type NO and NN in blood erythrocytes. Significantly higher level of GPA mutations type NO was registered in average in the group of exposed persons (23.2 +/- 4.6 x 10(-6)) compared with the control group (10.2 +/- 2.1 x 10(-6)) through the dose dependence was expressed slightly. The coefficient of the linear regression has equaled (2.3 +/- 1.2 x 10(-6)) Gy. The outlook on GPA assay usage in retrospective biodosimetry is discussed.
Databáze: OpenAIRE