Bufuralol, a new beta-adrenoceptor blocking agent. Part 1: synthesis and structure-activity studies in a series of benzofuran-2-ethanolamines

Autor:	G A, Fothergill, J M, Osbond, J C, Wickens
Rok vydání:	1977
Předmět:	Chemistry Structure-Activity Relationship Chemical Phenomena Ethanolamines Adrenergic beta-Antagonists Benzofurans
Zdroj:	Arzneimittel-Forschung. 27(5)
ISSN:	0004-4172
Popis:	The synthesis and resolution of a new beta-adrenoceptor blocking agent, 1-(7-ethylbenzofuran-2-yl)-2-tert.-butylamino-1-hydroxyethane (bufuralol) are described. Structure-activity studies leading to selection of the title compound are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ba00c3e6292cc2a52a34e7b373a4a9eb https://pubmed.ncbi.nlm.nih.gov/18158 Zobrazit plný text záznamu