Comparing three toothpastes in controlling plaque and gingivitis: A 6-month clinical study
| Autor: | Terdphong, Triratana, Petcharat, Kraivaphan, Cholticha, Amornchat, Luis R, Mateo, Boyce M, Morrison, Serge, Dibart, Yun-Po, Zhang |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Toothbrushing Adolescent Dental Plaque Phosphates Fluorides Young Adult Double-Blind Method Humans Dentifrices Aged Plant Extracts Dental Plaque Index Middle Aged Gingivitis Triclosan Sodium Bicarbonate Treatment Outcome Anti-Infective Agents Local Sodium Fluoride Female Periodontal Index Toothpastes Follow-Up Studies Phytotherapy |
| Zdroj: | American journal of dentistry. 28(2) |
| ISSN: | 0894-8275 |
| Popis: | To investigate the clinical efficacy of three toothpastes in controlling established gingivitis and plaque over 6 months.135 subjects were enrolled in a single-center, double-blind, parallel group, randomized clinical study. Subjects were randomly assigned to one of three treatments: triclosan/copolymer/fluoride dentifrice containing 0.3% triclosan, 2.0% copolymer and 1,450 ppm F as sodium fluoride in a silica base; herbal/bicarbonate dentifrice containing herbal extract and 1,400 ppm F as sodium fluoride in a sodium bicarbonate base; or fluoride dentifrice containing 450 ppm F as sodium fluoride, and 1,000 ppm F as sodium monofluorophosphate. Subjects were instructed to brush their teeth twice daily for 1 minute for 6 months.After 6 months, subjects assigned to the triclosan/copolymer/fluoride group exhibited statistically significant reductions in gingival index scores and plaque index scores as compared to subjects assigned to the herbal/bicarbonate group by 35.4% and 48.9%, respectively. There were no statistically significant differences in gingival index and plaque index between subjects in the herbal/ bicarbonate group and those in the fluoride group. The triclosan/copolymer/fluoride dentifrice was statistically significantly more effective in reducing gingivitis and dental plaque than the herbal/bicarbonate dentifrice, and this difference in efficacy was clinically meaningful. |
| Databáze: | OpenAIRE |
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