| Autor: |
A L R, Van De Velde, S, Anguille, Z N, Berneman |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Acta clinica Belgica. 67(6) |
| ISSN: |
1784-3286 |
| Popis: |
Therapeutic cancer vaccination, e.g. by using tumour antigen-presenting dendritic cells (DCs) that 'educate' the immune system to recognise and attack tumour cells, represents a new concept of treatment in oncology. DCbased immunotherapy elicits both innate (NK) and adaptive (T cells) cellular responses correlated with clinical benefit. WT1 mRNA-transfected DCs emerge as a feasible and effective strategy to control residual disease in acute myeloid leukaemia (AML), in particular as a post-remission treatment to prevent full relapse. This innovative approach takes advantage of the intrinsic potential of the immune system to eradicate malignant disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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