Enlargement of the thymus in a child with chronic granulomatous disease receiving interferon gamma therapy

Autor:	A P, Kourtis, C, Abramowsky, C, Ibegbu, L, Kobrynski
Rok vydání:	1998
Předmět:	CD4-Positive T-Lymphocytes Male Interferon-gamma Humans Leukocyte Common Antigens Radiography Thoracic Hypertrophy Thymus Gland Child Granulomatous Disease Chronic Tomography X-Ray Computed CD4 Lymphocyte Count
Zdroj:	Archives of pathologylaboratory medicine. 122(6)
ISSN:	0003-9985
Popis:	Both an enlarged thymus (with normal results on histologic examination) and an increase in the percentage of peripheral CD4+CD45RA+ (naive) T lymphocytes developed in a child with chronic granulomatous disease receiving long-term interferon gamma therapy. The thymic regrowth may be secondary to interferon gamma therapy or to overstimulation of his compromised immune system by recurrent infections. To our knowledge, an association between enlargement of the thymus and either chronic granulomatous disease or interferon gamma has not been previously reported.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b9e9704d67488726688ad642ee9afe64 https://pubmed.ncbi.nlm.nih.gov/9625428 Zobrazit plný text záznamu