| Autor: |
E, Jolivet, C, Plavonil, M, Sainte-Rose, B, Schaub |
| Jazyk: |
francouzština |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Journal de gynecologie, obstetrique et biologie de la reproduction. 45(9) |
| ISSN: |
1773-0430 |
| Popis: |
The aim of this study is to evaluate the screening for trisomy 21 (T21) between 2011 and 2013 on Martinique French West Indies after the decree of 23 June 2009.Were used the prenatal data provided by accredited laboratories and the data from the Registry of Congenital French West Indies (REMALAN).A total of 85.9 % of patients underwent screening: 60.5 % on a combined calculation of risk (CRC), 14.6 % on a sequential calculation of risk (CRS) and 10.8 % on serum markers 2nd trimester (MST2). Overall 5.4 % of the patients were placed in a risk group. During this period, 47 trisomy 21 were identified by the REMALAN which 38 (80.1 %) were detected prenatally: 24 of CRC, 3 on MST2 and 11 on signs of ultrasound at the 1st and 2nd trimester. The sensitivity of the CRC was 88 % for a false positive rate of 3.87 %. The overall sensitivity of screening (CRC, CRS and MST2) was 87 % for a false positive rate of 5.21 %.These data show that the coverage rate in Martinique is satisfactory and the screening fir Down syndrome meet expectations. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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