| Autor: |
C, Roussakis, Y F, Pouchus, C, Gratas, D, Riou, P, Dimou, G, Dabouis, S, Merle, J F, Verbist |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Anti-cancer drug design. 8(2) |
| ISSN: |
0266-9536 |
| Popis: |
Vinorelbine (NavelbineR) is a new antitumor agent chemically related to the Vinca alkaloid group, but differentiated by its in vivo activity relative to non-small-cell lung carcinoma (NSCLC). Studies in the NSCLC-bearing nude mouse of vinorelbine associations with drugs currently used clinically in phase III (cisplatin, 5-fluorouracil and actinomycin D) showed that such associations are ineffective or even of negative value and that it would be preferable to use vinorelbine alone in a single dose at the maximum tolerated concentration. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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