| Autor: |
P, Constant, F, Davodeau, M A, Peyrat, Y, Poquet, G, Puzo, M, Bonneville, J J, Fournié |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Science (New York, N.Y.). 264(5156) |
| ISSN: |
0036-8075 |
| Popis: |
Most human peripheral blood gamma delta T lymphocytes respond to hitherto unidentified mycobacterial antigens. Four ligands from Mycobacterium tuberculosis strain H37Rv that stimulated proliferation of a major human gamma delta T cell subset were isolated and partially characterized. One of these ligands, TUBag4, is a 5' triphosphorylated thymidine-containing compound, to which the three other stimulatory molecules are structurally related. These findings support the hypothesis that some gamma delta T cells recognize nonpeptidic ligands. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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