On the character of the nuclear membrane-associated DNA of HeLa cells
| Autor: | C D, Cabradilla, A P, Toliver |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Cell Nucleus
Chromatography Binding Sites Deoxyribonucleases Membranes DNA Repair DNA Centrifugation Isopycnic Sodium Chloride Cell Fractionation Nucleic Acid Denaturation Choline Ribonucleases Phospholipases Humans Carbon Radioisotopes Fluorouracil Deoxycholic Acid HeLa Cells Peptide Hydrolases Thymidine |
| Zdroj: | Physiological chemistry and physics. 7(2) |
| ISSN: | 0031-9325 |
| Popis: | The nature of the nascent DNA-membrane complexes isolated from synchronized HeLa cells was examined. It was found that membrane-associated DNA is not the result of repair replication. A study of the stability of the complexes to various degradative agents and enzymes suggest that the DNA is associated with a structure which is composed of a lipoprotein. An examination of the physical structure of this DNA indicates that it might be a "nicked" duplex with a base content similar to that of the bulk DNA. |
| Databáze: | OpenAIRE |
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