[Partial purification of tissue thromboplastin by the gel filtration method and its use for reproducing the generalized decompensated thrombinogenesis syndrome]

Autor:	Iu V, Magerovskiĭ, V A, Monastyrskiĭ, A V, Gaĭda, I I, Birka, M I, Voroniak
Rok vydání:	1988
Předmět:	Male Myocardium Chromatography Gel Animals Humans Blood Coagulation Tests Disseminated Intravascular Coagulation Kidney Rats Thromboplastin
Zdroj:	Voprosy meditsinskoi khimii. 34(3)
ISSN:	0042-8809
Popis:	Tissue thromboplastin was purified using various chromatographic resins: Sephadex G-200, Ultragel AcA 34, Acrylex P-300 and Toyopearl HW-55F. The purity of the preparations obtained was evaluated by means of the ratio of the thromboplastin solutions absorbency at 540 nm and a protein concentration in the solution expressed as mg/ml. The most purified preparations of tissue thromboplastin were obtained after gel filtration on Toyopearl HW-55F. The thromboplastin preparation produced was used for experimental reproduction of the syndrome of generalized decompensated thrombinogenesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b8fb365f2c1dd847323fbcf8fec5bcb9 https://pubmed.ncbi.nlm.nih.gov/3420807 Zobrazit plný text záznamu