Direct labeling of a somatostatin receptor antagonist via peptide cyclization with Re

Autor:	Jing, Wang, George, Makris, Marina, Kuchuk, Lauren, Radford, Fabio, Gallazzi, Michael R, Lewis, Silvia S, Jurisson, Heather M, Hennkens
Rok vydání:	2020
Předmět:	Radioisotopes Radiochemistry Rhenium Cyclization Isotope Labeling Animals Organotechnetium Compounds Receptors Somatostatin Peptides Rats
Zdroj:	Nuclear medicine and biology.
ISSN:	1872-9614
Popis:	With the long-term goal of developing a diagnostic (Re-1 was characterized by LC-ESI-MS and HR-ESI-MS and was tested for receptor affinity in SSTR-expressing cells (AR42J). Radiolabeling of the peptide was achieved via ligand exchange fromRe-1 consisted of two isomers, confirmed by LC-ESI-MS, with good SSTR2 affinity (ICNovelThe
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b8d8e99c609d16559db008fc7ed6c4ff https://pubmed.ncbi.nlm.nih.gov/33515899 Zobrazit plný text záznamu Full Text from ScienceDirect