Popis: |
To investigate the response of mice to concomitant infections with Trypanosoma brucei (Tb), Plasmodium berghei (Pb) and Heligmosomoides bakeri (Hb) infections. Each group of 6 mice was either infected with Pb + Tb + Hb, Pb + Tb, Pb + Hb, Tb + Hb, Pb, Tb, Hb or remained as uninfected controls. Hb infected mice each received 200 infective larvae (L3) of Hb orally, Tb infected mice each received 2 × 10−6 organisms through the intraperitoneal route while Pb infected mice received 1 × 10−5 parasitized red blood cells through the intraperitoneal route. PCV, body weights (BW), faecal egg counts (FEC), Tb parasitaemia, Pb parasitaemia, clinical signs and worm burdens (WB) were determined. FEC were highest in Pb + Tb + Hb and least in Hb group and the difference was significant (P |