Dietary determinants of aflatoxin B

Autor: Johanna Y, Andrews-Trevino, Patrick, Webb, Gerald, Shively, Beatrice, Rogers, Kedar, Baral, Dale, Davis, Krishna, Paudel, Ashish, Pokharel, Robin, Shrestha, Jia-Sheng, Wang, Kathy S, Xue, Shibani, Ghosh
Rok vydání: 2019
Předmět:
Zdroj: European Journal of Clinical Nutrition
ISSN: 1476-5640
Popis: Background Aflatoxins are found in diverse foods widely consumed worldwide. This study investigated the association between aflatoxin exposure and (a) consumption of specific foods, (b) dietary diversity (DD), and (c) seasonality. Methods Women enrolled in the AflaCohort Study in Banke, Nepal (n = 1648) were asked how often they ate certain food items in the past 7 days and 24 h. Serum aflatoxin B1-lysine (AFB1-lys) adduct levels, measured during pregnancy, were determined using high-performance liquid chromatography. Multivariable ordinary least squares and quantile regression models were used to examine incremental increases in AFB1-lys adduct levels per frequency of food consumption and the relationship between DD, seasonality, and increases in AFB1-lys adduct. Results Roughly 94% of women were exposed to aflatoxin (geometric mean 1.37 pg/mg). Women in the 30th, 50th, and 70th quantiles of aflatoxin exposure who reported one more occasion of maize consumption in the past week showed increases in AFB1-lys adduct levels: 0.094, 0.112, and 0.109 pg/mg (p
Databáze: OpenAIRE