Mammary tumors in feral mice lacking MuMTV DNA

Autor: M B, Gardner, R W, Malone, D W, Morris, L J, Young, R, Strange, R D, Cardiff, L J, Faulkin, D J, Mitchell
Rok vydání: 1985
Předmět:
Zdroj: Journal of experimental pathology. 2(2)
ISSN: 0730-8485
Popis: Two mammary tumors developed in feral mice treated with dimethylbenzanthracene. The tumors, livers, and spleens of these animals contained no MuMTV proviral DNA. Neither tumor had amplified or rearranged int-1 or int-2 loci. This demonstrates that mammary tumorigenesis can occur in mice in the absence of endogenous and exogenous MuMTV.
Databáze: OpenAIRE