Cytophilic activity of IgG2 from sera of guinea-pigs immunized with bovine gamma-globulin
| Autor: | R G, Leslie, S, Cohen |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Immunity
Cellular Macrophages Guinea Pigs Antigen-Antibody Complex Articles biochemical phenomena metabolism and nutrition Chromatography DEAE-Cellulose Iodine Radioisotopes Immunoglobulin G parasitic diseases Cell Adhesion Chromatography Gel Animals Chemical Precipitation Cattle Immunization Glass gamma-Globulins Antigens Immunoelectrophoresis Immunoglobulin Fragments |
| Zdroj: | Immunology. 27(4) |
| ISSN: | 0019-2805 |
| Popis: | IgG2 from immune guinea-pig sera collected 1-2 weeks after secondary BGG challenge showed considerably enhanced cytophilic activity; the preparations contained aggregates (±10 per cent of the total immunoglobulin) shown by antigen exchange to be immune complexes with a probable composition Ag (fragments) Ab5. After removal of aggregates the cytophilic activity of immune 7S IgG2 approximated that of IgG2 from unimmunized animals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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