| Autor: |
P, Sobrino García, A, García Pastor, A, García Arratibel, G, Vicente Peracho, P M, Rodriguez Cruz, J R, Pérez Sánchez, F, Díaz Otero, P, Vázquez Alén, J A, Villanueva Osorio, A, Gil Núñez |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Neurologia (Barcelona, Spain). 28(7) |
| ISSN: |
1578-1968 |
| Popis: |
The A-S-C-O classification may be better than other methods for classifying ischaemic stroke by aetiology. Our aims are to describe A-S-C-O phenotype distribution (A: atherosclerosis, S: small vessel disease, C: cardiac source, O: other causes; 1: potential cause, 2: causality uncertain, 3: unlikely to be a direct cause although disease is present) and compare them to the Spanish Society of Neurology's Cerebrovascular Disease Study Group (GEECV/SEN) classification. We will also find the degree of concordance between these classification methods and determine whether using the A-S-C-O classification delivers a smaller percentage of strokes of undetermined cause.We analysed those patients with ischaemic stroke admitted to our stroke unit in 2010 with strokes that were classified according to GEECV/SEN and A-S-C-O criteria.The study included 496 patients. The percentages of strokes caused by atherosclerosis and small vessel disease according to GEECV/SEN criteria were higher than the percentages for potential atherosclerotic stroke (A1) (14.1 vs. 11.9%; P=.16) and potential small vessel stroke (S1) (14.3 vs. 3%; P.001). Cardioembolic stroke (C1) was more frequent (22.2 vs. 31%; P.001). No differences between unusual cause of stroke and other potential causes (O1) were observed. Some degree of atherosclerosis was present in 53.5% of patients (A1, A2, or A3); 65.5% showed markers of small vessel disease (S1, S2, or S3), and 74.9% showed signs of cardioembolism (C1, C2, or C3). Fewer patients in the group without scores of 1 or 2 for any of the A-S-C-O phenotypes were identified as having a stroke of undetermined cause (46.6 vs. 29.2%; P.001). The agreement between the 2 classifications ranged from κ0.2 (small vessel and S1) to κ0.8 (unusual causes and O1).Our results show that GEECV/SEN and A-S-C-O classifications are neither fully comparable nor consistent. Using the A-S-C-O classification provided additional information on co-morbidities and delivered a smaller percentage of strokes classified as having an undetermined cause. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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