| Autor: |
D H, Marchand, K, Croes, J W, Dolan, L R, Snyder, R A, Henry, K M R, Kallury, S, Waite, P W, Carr |
| Rok vydání: |
2005 |
| Předmět: |
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| Zdroj: |
Journal of chromatography. A. 1062(1) |
| ISSN: |
0021-9673 |
| Popis: |
As reported previously, five solute-column interactions (hydrophobicity, steric resistance, hydrogen-bond acidity and basicity, ionic interaction) quantitatively describe column selectivity for 163 alkyl-silica, polar-group and cyano columns. In the present study, solute retention and column selectivity for 11 phenyl and 5 fluoro-substituted columns were compared with alkyl-silica columns of similar ligand length. It is concluded that two additional solute-column interactions may be significant in affecting retention and selectivity for the latter columns: (a) dispersion interactions of varying strength as a result of significant differences in bonded-phase polarizability or refractive index and (b) pi-pi interactions in the case of phenyl columns and aromatic solutes. These 16 phenyl and fluoro columns were also characterized in terms of hydrophobicity, steric resistance, hydrogen-bond acidity and basicity, and ionic interaction. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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