[Low-manifest infections in children and adolescents with consequences of perinatal damage of nervous system]
| Autor: | Iu I, Vaĭnshenker, O V, Kalinina, I V, Nuralova, I M, Ivchenko, L A, Meliucheva, V A, Tsinzerling |
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| Rok vydání: | 2012 |
| Předmět: |
Central Nervous System
Male Adolescent Coinfection Herpesviridae Infections Severity of Illness Index Mycoplasma Central Nervous System Bacterial Infections Pregnancy Child Preschool Chronic Disease Humans Brain Damage Chronic Female Chlamydia Pregnancy Complications Infectious Child Gram-Negative Bacterial Infections Ureaplasma urealyticum Herpesviridae |
| Zdroj: | Zhurnal mikrobiologii, epidemiologii i immunobiologii. (5) |
| ISSN: | 0372-9311 |
| Popis: | Study the specter of low-manifest infections (LMI) and their role in children and adolescents with diseases of central nervous system (CNS) against the background of consequences of perinatal damage of nervous system (PDNS).Infectologic and neurologic examinations were carried out in 42 patients with consequences of PDNS (17 girls and 25 boys, 3 - 15 years). Detection of LMI resulted in etiotropic therapy with evaluation of clinical and laboratory data in dynamics.In 93% (39/42) of patients causative agents of LMI were diagnosed in various combinations and in various biological materials. Among those: Chlamydia spp.--in 71% of patients, Mycoplasma spp.--in 31%, Ureaplasma urealyticum--in 14% (in total the listed microorganisms were diagnosed in 83% of patients); Herpesviridae family viruses--in 75% (HHV-6--in 67%, VEB--in 36%, CMV--in 11%, HSV-1,2--in 11%). Combination of Chlamydia spp. with HHV-6 (R tetr = +0.61) and with VEB (R tet = +0.74) (P0.05) was detected. None of the patients had typical signs of encephalitis clinically or based on MRT. MRT signs of gliosis-atrophic changes in the CNS were detected in all the patients. Reduction of a number of psycho-neurologic and neurologic syndromes was noted in all the patients during LMI therapy.Most of the patients with consequences of PDNS had low-intensity inflammatory-degenerative process in the CNS determined by LMI, first of all by Chlamydia spp. as well as Mycoplasma spp. |
| Databáze: | OpenAIRE |
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