[Influence of antenatal intermittent normobaric hypoxia during early organogenesis on the development of white rats]

Autor: L K, Trofimova, A V, Graf, M V, Maslova, T Iu, Dunaeva, Ia V, Krushinskaia, A S, Maklakova, A A, Baĭzhumanov, E N, Goncharenko, N A, Sokolova
Rok vydání: 2008
Předmět:
Zdroj: Izvestiia Akademii nauk. Seriia biologicheskaia. (3)
ISSN: 1026-3470
Popis: The influence of antenatal intermittent normobaric hypoxia during early organogenesis (days 9-10 of intrauterine development) on the physical development, vegetative balance, and antioxidant defense system of 60-day-old rats was studied. Antenatal exposure to intermittent hypoxia resulted in the impaired physical development of all offspring during the early 15-day postnatal period and caused changes in the vegetative balance of heart regulation, which were differently directed in males and females. Moreover, females that survived antenatal hypoxia had a decreased superoxide dismutase activity in the brain, compared to that in the control rats.
Databáze: OpenAIRE