| Autor: |
Kazunori, Nakaoka, Senju, Hashimoto, Naoto, Kawabe, Teiji, Kuzuya, Seiji, Yamada, Akira, Sawaki, Kohei, Funasaka, Mitsuo, Nagasaka, Yoshihito, Nakagawa, Ryoji, Miyahara, Tomoyuki, Shibata, Tetsuya, Tsukamoto, Yoshiki, Hirooka |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Clinical journal of gastroenterology. 15(1) |
| ISSN: |
1865-7265 |
| Popis: |
Pancreatic neuroendocrine neoplasms (PNENs) are relatively rare with a reported incidence of 1-2/100,000 and generally thought to originate from the precursor of the neuroendocrine cells including the islet and the pancreatic duct cells. About 65% of PNENs are non-functional. While insulinomas and gastrinomas are the most common functional PNENs, ACTH-producing PNENs are extremely rare. We herein present an extremely rare case of a patient with Cushing's syndrome caused by PNEN. A 46-year-old woman with edema in bilateral lower extremities and moon face was admitted with a suspicious pancreatic tumor. Enhanced computed tomography and endoscopic ultrasonography revealed a pancreatic tumor. The final diagnosis of ACTH-producing PNEN with Cushing's syndrome was based on clinical and biochemical test results and endocrinological studies. The symptoms associated Cushing's syndrome improved after pancreaticoduodenectomy for PNEN. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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