| Autor: |
R, Satterthwaite, S, Aswad, V, Sunga, H, Shidban, T, Bogaard, P, Asai, U, Khetan, I, Akra, R G, Mendez, R, Mendez |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Transplantation. 65(3) |
| ISSN: |
0041-1337 |
| Popis: |
In this study, we compare cholesterol levels during the first year after renal transplantation in FK506 (Prograf)- and cyclosporine-treated patients matched for cumulative first-year steroid dose and hypercholesterolemia risk factors. All patients had pretransplant cholesterol levels200 mg/dl. At 3 months posttransplant, 68% of the cyclosporine-treated patients had at least one cholesterol level greater than 200 mg/dl compared with 30% of the FK506-treated patients (P0.05). At the end of the year, 26% of FK506- and 67% of cyclosporine-treated patients remained hypercholesterolemic (P0.05). We conclude that cyclosporine has inherently more effect on cholesterol levels than FK506 during the first year after kidney transplantation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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