Protein profile of Helicobacter pylori strains by isoelectrofocusing in patients affected by chronic gastritis

Autor: S Paparo, Barbaro, G, Petrigni, F, Giovannelli, Fabio, Cerroni, A, Caroselli, R, De Rosa, C, Caroselli
Rok vydání: 2004
Předmět:
Zdroj: European review for medical and pharmacological sciences. 7(6)
ISSN: 1128-3602
Popis: To understand if relapse, following antimicrobial treatment was due to re-infection or to recrudescence.Fifty patients with dyspepsia were studied prospectively. They were followed up by endoscopy and biopsy of antral mucosa before and after treatment with anti-microbial therapy. Gel isoelectrofocusing was used to characterize protein profile of Hp.At baseline 40 patients were affected by chronic gastritis associated with Hp. At the end of treatment 75% patients given omeprazole, amoxicillin and clarithromycin were Hp infected: 43% showed the same protein profile and 57% different.Our data suggest that the relapse is due to recrudescence or to reinfection.
Databáze: OpenAIRE