| Popis: |
Natural killer (NK) cells, as professional cytotoxic cells, play a key role against cancer in the early and metastatic stages. Their functional defects are highly associated with the initiation or progression of breast cancer (BC). Here, we investigated the phenotypic characterization of NK cells in 26 newly diagnosed BC patients in comparison to 12 healthy counterparts.Expression of CXCR3 and PD-1, and also NKG2D, and TGF-βRII were studied on CD56Both CD56Our results demonstrated phenotypically suppressed-NK cells, especially in the CD56 |
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