Protectivity conferred by immunization with intranasal recombinant outer membrane protein H from Pasteurella multocida serovar A:1 in chickens
| Autor: | THANASARASAKULPONG, Arunee, POOLPERM, Pichayanut, TANKAEW, Pallop, SAWADA, Takuo, STHITMATEE, Nattawooti |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Pasteurella multocida
Full Paper Pasteurella Infections Bacteriology Antibodies Bacterial Recombinant Proteins Enterotoxins Adjuvants Immunologic Oligodeoxyribonucleotides recombinant outer membrane protein H intranasal vaccine Bacterial Vaccines Animals Chickens Administration Intranasal Bacterial Outer Membrane Proteins |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| Popis: | Recombinant outer membrane protein H (rOmpH) is a potential fowl cholera vaccine candidate. The present study was aimed at developing rOmpH formulations for intranasal administration. The rOmpH was purified and formulated with either Escherichia coli enterotoxin B (LTB) or CpG oligodeoxynucleotides (ODN) as an adjuvant. Antibody responses in chickens intranasally immunized with rOmpH in combination with 2 different adjuvants were significantly increased (P |
| Databáze: | OpenAIRE |
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