Refractory

Autor: Jessie, Chen, MaiAnh, Nguyen, Elaine, Cheong, D, Sean Riminton, Stephen, Reddel
Rok vydání: 2022
Zdroj: BMJ neurology open. 4(1)
ISSN: 2632-6140
Popis: A 39-year-old man with thymoma-associated acetylcholine receptor antibody myasthenia gravis (MG) presented with fevers, night sweats, abdominal pain and weight loss. Marked splenomegaly and intra-abdominal lymphadenopathy were found. Biopsies confirmed disseminatedThis case illustrates the autoimmune manifestations that can occur with thymoma. It illustrates the benefit of exogenous IFN-γ in overcoming the immune deficit. In this case, its use did not exacerbate existing autoimmune disease or trigger others. We raise awareness of the need to consider cytokine pathway defects as a contributing factor to refractory atypical infections in patients with thymoma-associated MG.
Databáze: OpenAIRE