Current concepts in immunosuppressive drug therapy of systemic lupus erythematosus

Autor:	T J, Lehman
Rok vydání:	1992
Předmět:	Glomerulonephritis Membranoproliferative Child Preschool Humans Lupus Erythematosus Systemic Precursor Cell Lymphoblastic Leukemia-Lymphoma Prognosis Cyclophosphamide Survival Analysis Immunosuppressive Agents
Zdroj:	The Journal of rheumatology. Supplement. 33
ISSN:	0380-0903
Popis:	The routine use of intravenous cyclophosphamide has led to advances in the preservation of renal function and quality of life for patients with systemic lupus erythematosus complicated by diffuse proliferative glomerulonephritis. Most patients receiving 3 years of intravenous cyclophosphamide according to a rigorous protocol experience longterm remission of their disease. However, in some the disease continues to progress or flares recurrently. Early intervention and combined immunosuppressive regimens modeled on protocols developed for the treatment of neoplastic disease appear to offer the greatest likelihood of attaining permanent remission for large numbers of patients. Pilot studies of these regimens are in progress.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b41f8b31634ae5011f9f8ff34013550b https://pubmed.ncbi.nlm.nih.gov/1593597 Zobrazit plný text záznamu