| Autor: |
Jian-she, Xu, Ji-wu, Yang, Miao-ning, Gu, Ye-ming, Chen |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 24(11) |
| ISSN: |
1000-2588 |
| Popis: |
To determine the effect of fentanyl on 50% effective concentration (EC50) of ropivacaine for postoperative epidural analgesia following gynecological surgery.Sixty-five patients (ASA class I to II) scheduled for elective gynecological surgery were randomly divided into two groups to receive 20 ml ropivacaine (group R, n=33) or ropivacaine combined fentanyl (group RF, n=32) for postoperative epidural analgesia. The concentration of ropivacaine was adjusted according to double-blinded up-down sequential allocation. The efficacy was assessed using visual analog scores (VAS) and EC50 calculated using method of Dixon.The EC50 of ropivacaine was 0.098% in group R and 0.069% in group RF, showing significant difference (P0.01).EC50 of ropivacaine for postoperative epidural analgesia determined by up-down sequential allocation is 0.098%, which can be decreased by the use of fentanyl. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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