Preparation and specificity of antibodies directed toward the ribose methylated nucleotide, 2'-O-methylguanosine 5'-monophosphate
Autor: | B S, Vold |
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Rok vydání: | 1981 |
Předmět: | |
Zdroj: | Biochimica et biophysica acta. 655(2) |
ISSN: | 0006-3002 |
Popis: | Antibodies have been produced that recognize the ribosome methylated nucleotide, 2'-O-methylguanosine 5'-monophosphate, pGm. Specificity was tested in a radioimmunoassay. Other ribose methylated nucleotides, deoxyguanosine, and guanosine 5'-monophosphate exhibited negligible cross-reactivity. Elements of antibody recognition, in descending order of importance, were the parent base, the methylated ribose moiety, and the phosphate group. |
Databáze: | OpenAIRE |
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