| Autor: |
V A, Matveeva, T E, Kliuchareva, E N, Uvarova |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 115(2) |
| ISSN: |
0365-9615 |
| Popis: |
Active PGE--secretion by malignant tumour cells of Syrian hamsters was demonstrated 30 min after their contact with NK-cells in vitro. The duration of PGE--secretion depended upon the ratio of tumour cells and NK--cells, engaged in contact. Increase of the number of NK--cells (bound to tumour cells) up to 10:1-20:1 led to rapid release of PGE from majority of tumour cells; in this case PGE release was continued not longer than 1.5-2.0 hours. The active release of PGE can be stopped after the contact of tumour and NK--cells by indomethacin at any moment of its secretion. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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