| Autor: |
Yin, Yang, Meaghan E, Story, Xingxing, Hao, Tina L, Sumpter, Alicia R, Mathers |
| Rok vydání: |
2021 |
| Zdroj: |
Frontiers in cell and developmental biology. 10 |
| ISSN: |
2296-634X |
| Popis: |
The purinergic receptor P2X7 (P2X7R) is important in inflammasome activation and generally considered to favor proinflammatory immune responses. However, there is still a limited understanding of the role of P2X7R signaling in Th cell differentiation, particularly, Th17 differentiation. Herein, the impact of P2X7R signaling on primary Th17 and Th1 cell responses was examined when P2X7R was expressed specifically on dendritic cells (DCs) and CD4 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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