| Autor: |
Chong-Jian, Wang, Nian-Hong, Yang, Ming-Jia, Xu, Song-Wen, Wu, Xuefeng, Yang, Liegang, Liu, Xiufa, Sun |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
Wei sheng yan jiu = Journal of hygiene research. 35(1) |
| ISSN: |
1000-8020 |
| Popis: |
To study the plasma concentration of peptide YY3 - 36 (PYY3-36) and the expression levels of PYY mRNA of ileum and colon in dietary induced obesity (DIO) and dietary induced obesity resistant (DIO-R) rats and the relation between PYY3-36 and DIO-R rats.Thirty-six female SD rats were randomly divided into high-fat diet group (n = 27) and chow fed control group (n = 9), after 13 weeks of either a high-fat diet or chew fed diet, the high-fat diet group was subdivided into DIO and DIO-R group according to the final body weight. Weight gain, caloric intake, the concentration of PYY3-36 and the expression levels of PYY mRNA were measured and compared.The total caloric intake of DIO-R rats was lower than DIO rats (P0.01), while no significant difference was found between DIO-R and control rats (P0.05). The concentration of PYY3-36 and the expressions of PYY mRNA of ileum and colon in DIO-R rats were higher significantly than that of the DIO and control rats (P0.01), while no significant difference was found between DIO and control group (P0.05), except that PYY mRNA of ileum was advanced in DIO group (P0.01).On the High-fat diet, SD rats showed different susceptibility to obese and energy intake, increased levels of PYY3-36 and PYY mRNA might be related to dietary induced obesity resistant. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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