Re-irradiation of recurrent head and neck carcinomas: comparison of robust intensity modulated proton therapy treatment plans with helical tomotherapy
Autor: | Martin, Stuschke, Andreas, Kaiser, Jehad, Abu-Jawad, Christoph, Pöttgen, Sabine, Levegrün, Jonathan, Farr |
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Rok vydání: | 2013 |
Předmět: |
Squamous Cell Carcinoma of Head and Neck
Radiotherapy Planning Computer-Assisted Research IMPT Helical tomotherapy Head and Neck Neoplasms Carcinoma Squamous Cell Proton Therapy Humans Intensity modulated proton therapy Plan comparison Re-irradiation Radiotherapy Intensity-Modulated Neoplasm Recurrence Local Robust optimization Robustness |
Zdroj: | Radiation Oncology (London, England) |
ISSN: | 1748-717X |
Popis: | Background To test the hypothesis that the therapeutic ratio of intensity-modulated photon therapy using helical tomotherapy (HT) for retreatment of head and neck carcinomas can be improved by robust intensity-modulated proton therapy (IMPT). Methods Comparative dose planning with robust IMPT was performed for 7 patients retreated with HT. Results On average, HT yielded dose gradients steeper in a distance ≤ 7.5 mm outside the target (p |
Databáze: | OpenAIRE |
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