Methods for Ex Vivo Analysis of Immune Cell Function from the Central Nervous System

Autor: Darryl G, Turner, Melanie D, Leech, Richard A, O'Connor, Stephen M, Anderton
Rok vydání: 2015
Předmět:
Zdroj: Methods in molecular biology (Clifton, N.J.). 1304
ISSN: 1940-6029
Popis: Experimental autoimmune encephalomyelitis (EAE) is an animal model commonly used to investigate the inflammatory response in organ-specific autoimmunity and a model of the early immune responses of multiple sclerosis.This protocol outlines the methods used for the processing of peripheral immune tissues, the spleen and draining lymph nodes, as well as the site of inflammation, the central nervous system (CNS), for analyzing immune cell phenotype and function during murine EAE.
Databáze: OpenAIRE