Type D SRV-2 virus-specific CD8+ and CD4- CD8- T cells that regulate virus-induced T cell proliferation in Celebes macaques

Autor: A, Malley, N, Pangares, S K, Mayo, M, Zeleny-Pooley, J V, Torres, E, Benjamin, M K, Axthelm
Rok vydání: 1993
Předmět:
Zdroj: Journal of medical primatology. 22(2-3)
ISSN: 0047-2565
Popis: These studies defined SRV-2 envelope peptides 96-102, 127-152, and 233-249 as T cell epitopes that induce significant T cell proliferation. Peripheral blood lymphocytes of Celebes macaques (Macaca nigra) exposed to SRV-2 and currently virus- antibody+, cultured with SRV-2 virus show strongly suppressed T cell responses and have two immunoregulatory T cell populations.
Databáze: OpenAIRE