[The composition and drug sensitivity of a mycobacterial population in patients with suspected tuberculosis]

Autor: I R, Dorozhkova, M V, Badleeva, O I, Skotnikova, E Iu, Nosova, E A, Kupavtseva, S E, Borisov, A M, Moroz
Rok vydání: 2005
Předmět:
Zdroj: Problemy tuberkuleza i boleznei legkikh. (8)
ISSN: 1728-2993
Popis: By using the diagnostic material (175 sputum samples and 103 bronchoalveolar lavage fluid samples) taken from 39 patients with suspected tuberculous infection during a 2.5-month follow-up, the authors traced the time course of changes in the composition and drug sensitivity of a mycobacterial population to rifampicin. Along with the traditional microbiological studies, the latest molecular biological studies, a TB-BIOCHIP test system (enzyme immunoassay) in particular, were employed to detect the bacterial and L-transformed forms of the causative agent. A molecular biological assay was first developed to detect the drug sensitivity of L-forms of Mycobacterium tuberculosis.
Databáze: OpenAIRE