| Autor: |
Sarah L, Lawrence, David, Grynspan, Monica, Chan, Julie, Hurteau, C L Elizabeth, Nizalik, Franco, Momoli, Emanuela, Ferretti |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Journal of perinatology : official journal of the California Perinatal Association. 40(6) |
| ISSN: |
1476-5543 |
| Popis: |
The objective of this study is to determine whether rapidity of death in necrotizing enterocolitis (NEC) increased odds of discordance between clinical and pathological diagnosis.Retrospective case-series study including preterm infants admitted to the NICU.Twenty-two infants met the selection criteria. Gross pathologic evidence of NEC was present in 1/6 cases (17%) where demise occurred12 h after onset of symptoms, 3/5 cases (60%) within 12-24 h, and 8/11 cases (73%) in24 h. Histological evidence of necrosis was present in 4/6 (67%) cases when death occurred12 h, 4/5 (80%) in 12-24 h, and 9/11 (82%) in24 h. The percentage with gross pathologic evidence showed a monotonic trend (P = 0.031), while the trend was less clear for histologic findings (P = 0.496).Pathologic features of cell death may not have had sufficient time to develop. This study could reassure both healthcare providers and families when pathologic and clinical diagnoses are not consistent. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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