Mandible metastasis as the first sign from primary adenocarcinoma of the lung

Autor: Valfrido Antonio, Pereira-Filho, Marcelo Donizetti, Chaves, Jorge, Haddad, Mario Francisco Real, Gabrielli, Marisa Aparecida Cabrini, Gabrielli, Eduardo, Hochulli-Vieira, Pablo Agustin, Vargas
Rok vydání: 2007
Předmět:
Zdroj: General dentistry. 55(3)
ISSN: 0363-6771
Popis: Adenocarcinoma of the lung that metastasizes to the mandible is very uncommon; only a few cases have been described in the English-language literature. This article presents a metastasis from adenocarcinoma of the lung affecting the mandible of a 64-year-old woman, in which the first discovered metastatic lesion was detected before the primary tumor. The immunoreactivity for human thyroid transcription factor-1 (TTF-1) in the oral lesion was essential for determining the site and type of the primary tumor, as the patient showed no clinical or radiographic evidence of a tumor in the thyroid gland. After the primary tumor in the lung was diagnosed, radiotherapy and chemotherapy were initiated; unfortunately, the patient died two months after the start of treatment. This article emphasizes the importance of a well-conducted examination for diagnosing metastatic oral lesions.
Databáze: OpenAIRE