| Autor: |
O K, Kutitova, G Iu, Lipskaia, S V, Maslova, V I, Agol |
| Rok vydání: |
1989 |
| Předmět: |
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| Zdroj: |
Molekuliarnaia genetika, mikrobiologiia i virusologiia. (11) |
| ISSN: |
0208-0613 |
| Popis: |
Oligonucleotide maps of some poliovirus type 2 strains isolated from polio cases, while being clearly related to that of the Sabin vaccine type 2 strain, exhibited, nevertheless, marked differences from the reference (vaccine) map. Several large oligonucleotides derived from 4 such strains were subjected to enzymatic sequencing. The results strongly suggest that all of them were intertypic recombinants between the Sabin strains. The 5'-parts of the genomes of these strains were derived from the type 2 vaccine whereas the 3'-parts were of type 1 (in 2 strains) or type 3 (in other 2 strains) origin. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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