[Biological vascularized matrix (BioVaM): a new method for solving the perfusion problems in tissue engineering]

Autor:	D, Schultheiss, A I, Gabouev, P M, Kaufmann, N, Schlote, H, Mertsching, A, Haverich, C G, Stief, U, Jonas
Jazyk:	němčina
Rok vydání:	2004
Předmět:	Bioartificial Organs Tissue Engineering Swine Reperfusion Injury Urinary Bladder Cell Culture Techniques Animals Endothelial Cells Neovascularization Physiologic Cells Cultured Extracellular Matrix
Zdroj:	Der Urologe. Ausg. A. 43(10)
ISSN:	0340-2592
Popis:	A new technique is presented to harvest an acellular matrix from a porcine small bowel segment preserving the mesenteric arterial and venous pedicles. Reseeding of this biological vascularized matrix (BioVaM) with functional cells, i.e. smooth muscle and urothelial cells isolated from the urinary tract, and resurfacing of its vascular structures with endothelial precursor cells results in a vascularized tissue engineered graft for reconstruction and augmentation of the urinary bladder. First promising short term implantation experiments using a porcine model for the evaluation of early graft perfusion after vascular anastomosis are presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b226caf69720bbdc4d49475eb09d2ae1 https://pubmed.ncbi.nlm.nih.gov/15549160 Zobrazit plný text záznamu Full text from SpringerLink