Expression and prognostic significance of heat-shock proteins in myelodysplastic syndromes
| Autor: | Amélie, Duval, Daniela, Olaru, Lydia, Campos, Pascale, Flandrin, Nathalie, Nadal, Denis, Guyotat |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Aged 80 and over Male ATP Binding Cassette Transporter Subfamily B bcl-X Protein Antigens CD34 Apoptosis Middle Aged Flow Cytometry Prognosis Severity of Illness Index Survival Analysis Genes bcl-2 Hematopoiesis Gene Expression Regulation Proto-Oncogene Proteins c-bcl-2 Leukemia Myeloid Myelodysplastic Syndromes Acute Disease Disease Progression Humans Female Heat-Shock Proteins Aged Glycoproteins |
| Zdroj: | Haematologica. 91(5) |
| ISSN: | 1592-8721 |
| Popis: | Using flow cytometry, we investigated the clinical and hematologic relevance of expression of heat-shock proteins (HSP) HSP27, HSP60, HSP70, HSP90 and HSP110 in bone marrow of 142 patients with newly diagnosed myelodysplastic syndromes, together with that of the membrane differentiation antigen CD34 and the drug-resistance related protein, P170 (Pgp). |
| Databáze: | OpenAIRE |
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