| Autor: |
T M, O'Connor, D, Cagney, A, Jahangir, A, Brady, J, Fitzgibbon, G, Lee, A, El-Gammal, N J, Brennan |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Irish medical journal. 102(6) |
| ISSN: |
0332-3102 |
| Popis: |
We explored the relationship between erythema nodosum (EN) and sex, age, serum angiotensin converting enzyme (ACE), bronchoalveolar lavage lymphocytosis (BAL-I), interstitial granulomas and radiological stage in patients presenting with pulmonary sarcoidosis in Ireland. Sixty-nine patients diagnosed with sarcoidosis between 2003 and 2006 were studied. Forty one patients (59%) were male. Sixteen patients (23%) presented with EN. Forty one patients of 65 (63%) had transbronchial biopsies demonstrating non-caseating granulomas. Patients with sarcoidosis presenting with EN were more likely to be female (p=0.042), younger (p=0.012) and have earlier stage pulmonary disease (p=0.02). There were no correlations between serum ACE, interstitial granulomas and disease stage. BAL-I did however predict increasing disease radiological stage (p=0.042). In this study, one quarter of patients with sarcoidosis presented with EN among their presenting features. These patients were more likely to be young females with early stage radiological disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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