Malignant cutaneous melanoma associated with neurofibromatosis in two sisters from a family with familial atypical multiple mole melanoma syndrome. Case reports and review of the literature

Autor:	M P, Stokkel, B B, Kroon, J J, van der Sande, H, Neering
Rok vydání:	1993
Předmět:	Adult Neoplasms Multiple Primary Neurofibromatosis 1 Skin Neoplasms Humans Female Dysplastic Nevus Syndrome Melanoma
Zdroj:	Cancer. 72(8)
ISSN:	0008-543X
Popis:	Two cases of malignant melanoma associated with neurofibromatosis in two first-degree female relatives from a family with familial atypical multiple mole melanoma (FAMMM) syndrome are presented. The types of neurofibromatosis and the FAMMM syndrome are discussed in relation to these cases and the family genealogic tree. Although the FAMMM syndrome could probably be seen as the underlying disease in the current cases, review of literature has failed to establish a clear relation. Research into pigmentary disturbance in neurofibromatosis is necessary to give a final explanation. To our knowledge, this is the first report in literature describing the familial occurrence of both diseases and it might present an addition to the tumor spectrum in the FAMMM syndrome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b18fe9bc98953ae8d291e43fd87fada4 https://pubmed.ncbi.nlm.nih.gov/8402451 Zobrazit plný text záznamu Plný text