High prevalence of type 2 diabetes in all ethnic groups, including Europeans, in a British inner city: relative poverty, history, inactivity, or 21st century Europe?
| Autor: | L, Riste, F, Khan, K, Cruickshank |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Urban Population Black People White People Body Mass Index Ethnicity Humans Mass Screening Pakistan Poverty Aged Body Weight Glucose Tolerance Test Middle Aged Body Height United Kingdom Europe Caribbean Region Diabetes Mellitus Type 2 England Data Interpretation Statistical Africa Income Educational Status Female |
| Zdroj: | Diabetes care. 24(8) |
| ISSN: | 0149-5992 |
| Popis: | To compare the prevalence of type 2 diabetes in white Europeans and individuals of African-Caribbean and Pakistani descent.Random sampling of population-based registers in inner-city Manchester, Britain's third most impoverished area. A total of 1,318 people (25-79 years of age) were screened (minimum response 67%); 533 individuals without known diabetes underwent 2-h glucose tolerance testing, classified by 1999 World Health Organization criteria.More than 60% of individuals reported household annual incomepound10,000 ($15,000) per year. Energetic physical activity was rare and obesity was common. Age-standardized (35-79 years) prevalence (mean 95% CI) of known and newly detected diabetes was 20% (17-24%) in Europeans, 22% (18-26%) in African-Caribbeans, and 33% (25-41%) in Pakistanis. Minimum prevalence (assuming all individuals not tested were normoglycemic) was 11% (8-14%), 19% (15-23%), and 32% (24-40%), respectively. Marked changes in prevalence represent only small shifts in glucose distributions. Regression models showed that greater waist girth, lower height, and older age were independently related to plasma glucose levels, as was physical activity. Substituting BMI and waist-to-hip ratio revealed their powerful contribution.A surprisingly high prevalence of diabetes, despite expected increases with new lower criteria, was found in Europeans, as previously established in Caribbeans and Pakistanis. Lower height eliminated ethnic differences in regression models. History and relative poverty, which cosegregate with obesity and physical inactivity, are likely contributors. Whatever the causes, the implications for health services are alarming, although substantial preventive opportunities through small reversals of glucose distributions are the challenge. |
| Databáze: | OpenAIRE |
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