[Detection of TCR-gamma chain gene rearrangement in malignant histiocytosis]

Autor: Chang-li, Lu, Gan-di, Li, Wei-ping, Liu, Jia, Guo, Feng-yuan, Li, Dian-ying, Liao, Wen-yan, Zhang
Rok vydání: 2004
Předmět:
Zdroj: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 25(4)
ISSN: 0253-2727
Popis: To investigate the lineage of the malignant cells in malignant histiocytosis.Polymerase chain reaction with two groups of common primers for TCR-gamma gene was used to analyze the malignant cells of 28 autopsied cases of malignant histiocytosis.Monoclonal TCR-gamma gene rearrangements were detected in 12 out of the 28 samples (43%).Most cases diagnosed as malignant histiocytosis in Southwest China seems to be peripheral T-cell lymphomas.
Databáze: OpenAIRE