Circulating 25-Hydroxyvitamin D and Risk of Esophageal and Gastric Cancer

Autor:	Abnet, Christian C., Chen, Yu, Chow, Wong-Ho, Gao, Yu-Tang, Helzlsouer, Kathy J., Le Marchand, Loïc, McCullough, Marjorie L., Shikany, James M., Virtamo, Jarmo, Weinstein, Stephanie J., Xiang, Yong-Bing, Yu, Kai, Zheng, Wei, Albanes, Demetrius, Arslan, Alan A., Campbell, David S., Campbell, Peter T., Hayes, Richard B., Horst, Ronald L., Kolonel, Laurence N., Nomura, Abraham M. Y., Purdue, Mark P., Snyder, Kirk, Shu, Xiao-Ou
Jazyk:	angličtina
Rok vydání:	2010
Předmět:	Adult Male China stomach neoplasms Esophageal Neoplasms Original Contributions case-control studies vitamin D Vitamin D Deficiency prospective studies United States Cohort Studies Logistic Models Risk Factors Humans Female Finland
Zdroj:	American Journal of Epidemiology
ISSN:	1476-6256 0002-9262
Popis:	Upper gastrointestinal (GI) cancers of the stomach and esophagus have high incidence and mortality worldwide, but they are uncommon in Western countries. Little information exists on the association between vitamin D and risk of upper GI cancers. This study examined the association between circulating 25-hydroxyvitamin D (25(OH)D) and upper GI cancer risk in the Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Concentrations of 25(OH)D were measured from 1,065 upper GI cancer cases and 1,066 age-, sex-, race-, and season-of blood draw–matched controls from 8 prospective cohort studies. In multivariate-adjusted models, circulating 25(OH)D concentration was not significantly associated with upper GI cancer risk. Subgroup analysis by race showed that among Asians, but not Caucasians, lower concentrations of 25(OH)D (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::b167ed53ad244f72eaa6a216749dfec5 http://europepmc.org/articles/PMC2892544 Zobrazit plný text záznamu